13. Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain
Kelsey H. Collins, Kristin L. Lenz, Hope D. Welhaven, Erica Ely, Luke E. Springer, Sophie Paradi, Ruhang Tang, Lauryn Braxton, Antonina Akk, Huimin Yan, Bo Zhang, Xiaobo Wu, John P. Atkinson, Arin K. Oestreich, Ron K. June, Christine T. N. Pham, and Farshid Guilak.
Sci. Adv. 11, eadt5915 (2025).
12. Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury
Bergman RF, Lammlin L, Junginger L, Farrell E, Goldman S, Darcy R, Rasner C, Obeidat AM, Malfait AM, Miller RE, Maerz T.
Osteoarthritis Cartilage. 2024 Jul
Preprint out now: View Article
11. Charge-Reversed Exosomes for Targeted Gene Delivery to Cartilage for Osteoarthritis Treatment
C. Zhang, T.V. Pathrikar, HM Baby, J. Li, H. Zhang, A. Selvadoss, A. Ovchinnikova, A. Ionescu, S. Chubinskaya, RE Miller, A.G. Bajpayee.
Small Methods. 2024 April
10. Reduced Capsaicin-Induced Mechanical Allodynia and Neuronal Responses in the DRG in the Presence of Ptpn6 Overexpression
Vroman R, Ishihara S, Fullam S, Wood MJ, Adamczyk NS, Lomeli N, Malfait F, Malfait AM, Miller RE, Markovics A.
Mol Pain. 2024 May 16.
View Article
9. The Mas-related G protein-coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy
George DS, Jayaraj ND, Pacifico P, Ren D, Sriram N, Miller RE, Malfait AM, Miller RJ, Menichella DM.
Pain. 2024 May 1;165(5):1154-1168.
View Article
8. Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
Bai Z, Bartelo N, Aslam M, Murphy EA, Hale CR, Blachere NE, Parveen S, Spolaore E, DiCarlo E, Gravallese EM, Smith MH; Accelerating Medicines Partnership RA/SLE Network; Frank MO, Jiang CS, Zhang H, Pyrgaki C, Lewis MJ, Sikandar S, Pitzalis C, Lesnak JB, Mazhar K, Price TJ, Malfait AM, Miller RE, Zhang F, Goodman S, Darnell RB, Wang F, Orange DE.
Sci Transl Med. 2024 Apr 10;16(742):eadk3506.
View Article
7. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model.
Lai A, Iliff D, Zaheer K, Gansau J, Laudier DM, Zachariou V, Iatridis JC.
Int J Mol Sci. 2024 Feb 1, 25(3):1762
P30 Funded Publication
View Article
6. Diverse Response to Local Pharmacological Blockade of Sirt1 Cleavage in Age-Induced versus Trauma-Induced Osteoarthritis Female Mice.
Maatuf YH, Marco M, Unger-Gelaman S, Farhart E, Zobrab A, Roy A, Kumar A, Carmon I, Reich E, Dvir-Ginzverg M.
Biomolecules 2024, 14(1), 81
View Article
5. Sensory profiling in classical Ehlers-Danlos syndrome: a case-control study revealing pain characteristics, somatosensory changes, and impaired pain modulation
Colman M, Syx D, de Wandele I, Rombaut L, Wilie D, Malfait Z, Meeus M, Malfait AM, Van Oosterwijck J, Malfait F.
medRxiv [Preprint]. 2023 Feb 26, Update in: J Pain. 2023 Nov;24(11):2063-2078
P30 Funded Publication
View Article
4. Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behaviours.
Courties A, Olmer M, Myers K, Ordoukhanian P, Head SR, Natarajan P, Berenbaum F, Sellam J, Lotz MK.
Ann Rheum Dis. 2023
View Article
3. Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis.
Obeidat AM, Wood MJ, Adamczyk NS, Ishihara S, Li J, Wang L, Ren D, Bennett DA, Miller RJ, Malfait AM, Miller RE.
Nat Commun. 2023 Apr 29
View Article
2. Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain.
Lai Wang, Shingo Ishihara, Jun Li, Rachel E Miller, Anne-Marie Malfait.
Arthritis Res Ther 25, 63 (2023)
View Article
1. Age-associated changes in knee osteoarthritis, pain-related behaviors, and dorsal root ganglia immunophenotyping of male and female mice.
Geraghty, T., Obeidat, A.M., Ishihara, S., Wood, M.J., Li, J., Lopes, E.B.P., Scanzello, C.R., Griffin, T.M., Malfait, A.-M. and Miller, R.E. Arthritis and Rheumatology 2023
View Article